Based on advice here I did add a dehumidifier upstairs and on very hot days I run it and the air conditioner at the same time. Electric bill has been very high this summer, but the upstairs is finally livable.
I'm happy with both of these units I bought this year:
Basement: Frigidaire 35 pints.
https://www.homedepot.com/p/Frigidai...33W1/312539821
Upstairs: GE 22 pints.
https://www.homedepot.com/p/GE-22-pt...22LA/315445853 Pretty noisy, so don't plan on running it in your bedroom at night.
I had to get a lighter unit for upstairs to be able to carry it up the stairs. I assume a basement would be more humid than the upstairs, hence the higher capacity bucket for the basement. I empty each bucket once a day and that seems sufficient to keep the humidity at around 50%.
The biggest concern with these machines is the high number of reviews that say they last only a couple of years.