Typically you follow the suggested route line (see it on the left side).
Also watch for the dashed line that surrounds the markers in the middle, these mean not to pass between these buoys/markers. Click on that dashed line and it should say something similar to 'stay clear of the buoys surrounded by the dashed line'.
Here is the area you're asking about
:
https://webapp.navionics.com/?lang=e...key=wyhiGp_urL
If you wanted to go up the east side of this area, you could pass to the west of the red top and the east of the black top that is to the north west corner of Jolly Island, but you can see the suggested route on the west side of this area. It looks like the chart is suggesting not to go up the middle.